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  1. Glioblastoma Multiforme, an aggressive primary brain tumor, has a poor prognosis and no effective standard of care treatments. Most patients undergoing radiotherapy, along with Temozolomide chemotherapy, devel...

    Authors: Radhika Saraf, Shaghayegh Agah, Aniruddha Datta and Xiaoqian Jiang

    Citation: BMC Biomedical Engineering 2021 3:7

    Content type: Research article

    Published on:

  2. Organoids are a reliable model used in the study of human brain development and under pathological conditions. However, current methods for brain organoid culture generate tissues that range from 0.5 to 2 mm o...

    Authors: Mariana Oksdath Mansilla, Camilo Salazar-Hernandez, Sally L. Perrin, Kaitlin G. Scheer, Gökhan Cildir, John Toubia, Kristyna Sedivakova, Melinda N. Tea, Sakthi Lenin, Elise Ponthier, Erica C. F. Yeo, Vinay Tergaonkar, Santosh Poonnoose, Rebecca J. Ormsby, Stuart M. Pitson, Michael P. Brown…

    Citation: BMC Biomedical Engineering 2021 3:6

    Content type: Methodology article

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  3. End-stage heart failure is a major risk of mortality. The conductive super-aligned carbon nanotubes sheets (SA-CNTs) has been applied to restore the structure and function of injured myocardium through tissue ...

    Authors: Quanfu Xu, Yuli Yang, Jianwen Hou, Taizhong Chen, Yudong Fei, Qian Wang, Qing Zhou, Wei Li, Jing Ren and Yi-Gang Li

    Citation: BMC Biomedical Engineering 2021 3:5

    Content type: Research article

    Published on:

  4. Liver cancer is the sixth most common cancer worldwide. It is mostly diagnosed with a computed tomography scan. Nowadays deep learning methods have been used for the segmentation of the liver and its tumor fro...

    Authors: Yodit Abebe Ayalew, Kinde Anlay Fante and Mohammed Aliy Mohammed

    Citation: BMC Biomedical Engineering 2021 3:4

    Content type: Research article

    Published on:

  5. Magnetic Resonance Imaging (MRI), a non-invasive method for the diagnosis of diverse health conditions has experienced growing popularity over other imaging modalities like ultrasound and Computer Tomography. ...

    Authors: Faith Natukunda, Theodora M. Twongyirwe, Steven J. Schiff and Johnes Obungoloch

    Citation: BMC Biomedical Engineering 2021 3:3

    Content type: Review

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  7. Electric fields are involved in numerous physiological processes, including directional embryonic development and wound healing following injury. To study these processes in vitro and/or to harness electric fi...

    Authors: Christina N. M. Ryan, Meletios N. Doulgkeroglou and Dimitrios I. Zeugolis

    Citation: BMC Biomedical Engineering 2021 3:1

    Content type: Review

    Published on:

  8. Bismuth compounds are known for their activity against multiple microorganisms; yet, the antibiotic properties of bismuth nanoparticles (BiNPs) remain poorly explored. The objective of this work is to further ...

    Authors: Roberto Vazquez-Munoz, M. Josefina Arellano-Jimenez and Jose L. Lopez-Ribot

    Citation: BMC Biomedical Engineering 2020 2:11

    Content type: Research article

    Published on:

  9. A major challenge for any glaucoma implant is their ability to provide long-term intraocular pressure lowering efficacy. The formation of a low-permeability fibrous capsule around the device often leads to obs...

    Authors: Ian Grierson, Don Minckler, Marian K. Rippy, Andrew J. Marshall, Nathalie Collignon, Jessica Bianco, Benoit Detry and Murray A. Johnstone

    Citation: BMC Biomedical Engineering 2020 2:10

    Content type: Research article

    Published on:

  11. High occupational physical activity is associated with lower health. Shoe-based movement sensors can provide an objective measurement of occupational physical activity in a lab setting but the performance of s...

    Authors: Jonatan Fridolfsson, Daniel Arvidsson, Frithjof Doerks, Theresa J. Kreidler and Stefan Grau

    Citation: BMC Biomedical Engineering 2020 2:8

    Content type: Research article

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  12. Tourniquets in orthopaedic surgery safely provide blood free surgical fields, but their use is not without risk. Tourniquets can result in temporary or permanent injury to underlying nerves, muscles, blood ves...

    Authors: Bassam A. Masri, Andrew Eisen, Clive P. Duncan and James A. McEwen

    Citation: BMC Biomedical Engineering 2020 2:7

    Content type: Review

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  15. CS-MRI (compressed sensing for magnetic resonance imaging) exploits image sparsity properties to reconstruct MRI from very few Fourier k-space measurements. Due to imperfect modelings in the inverse imaging, s...

    Authors: Liyan Sun, Yawen Wu, Zhiwen Fan, Xinghao Ding, Yue Huang and John Paisley

    Citation: BMC Biomedical Engineering 2020 2:4

    Content type: Research Article

    Published on:

  16. The characterization of limb biomechanics has broad implications for analyzing and managing motion in aging, sports, and disease. Motion capture videography and on-body wearable sensors are powerful tools for ...

    Authors: Kaitlyn R. Ammann, Touhid Ahamed, Alice L. Sweedo, Roozbeh Ghaffari, Yonatan E. Weiner, Rebecca C. Slepian, Hongki Jo and Marvin J. Slepian

    Citation: BMC Biomedical Engineering 2020 2:3

    Content type: Research article

    Published on:

  18. Strength and coordination of lower muscle groups typically identified in healthy subjects are two prerequisites to performing functional activities. These physical qualities can be impaired following a neurolo...

    Authors: Mathieu Lalumiere, Cloé Villeneuve, Cassandra Bellavance, Michel Goyette and Daniel Bourbonnais

    Citation: BMC Biomedical Engineering 2020 2:1

    Content type: Methodology article

    Published on:

  20. In the original publication of this article [1] the figures and captions were linked incorrectly. In this correction article the figures & captions are correctly published.

    Authors: Sylvia Müller, Lyndsey Nicholson, Naif Al Harbi, Elena Mancuso, Elena Jones, Anne Dickinson, Xiao Nong Wang and Kenneth Dalgarno

    Citation: BMC Biomedical Engineering 2019 1:34

    Content type: Correction

    Published on:

    The original article was published in BMC Biomedical Engineering 2019 1:16

  21. Arm support devices are available to support people with Duchenne muscular dystrophy (DMD), but active trunk support devices are lacking. An active trunk support device can potentially extend the reach of the ...

    Authors: Stergios Verros, Laura Peeters, Arjen Bergsma, Edsko E. G. Hekman, Gijsbertus J. Verkerke and Bart F. J. M. Koopman

    Citation: BMC Biomedical Engineering 2019 1:31

    Content type: Research article

    Published on:

  22. Muscles contain contractile and (visco-) elastic passive components. At the latest since Hill’s classic works in the 1930s, it has been known that these elastic components affect the length and rate of change ...

    Authors: Walter Herzog

    Citation: BMC Biomedical Engineering 2019 1:28

    Content type: Review

    Published on:

  23. Tendons link muscle to bone and transfer forces necessary for normal movement. Tendon injuries can be debilitating and their intrinsic healing potential is limited. These challenges have motivated the developm...

    Authors: Sophia K. Theodossiou and Nathan R. Schiele

    Citation: BMC Biomedical Engineering 2019 1:32

    Content type: Review

    Published on:

  24. Hybrid exoskeletons are a recent development which combine Functional Electrical Stimulation with actuators to improve both the mental and physical rehabilitation of stroke patients. Hybrid exoskeletons have b...

    Authors: Ashley Stewart, Christopher Pretty and Xiaoqi Chen

    Citation: BMC Biomedical Engineering 2019 1:30

    Content type: Research article

    Published on:

  25. Triple tracer meal experiments used to investigate organ glucose-insulin dynamics, such as endogenous glucose production (EGP) of the liver are labor intensive and expensive. A procedure was developed to obtai...

    Authors: Mariël F. van Stee, Shaji Krishnan, Albert K. Groen and Albert A. de Graaf

    Citation: BMC Biomedical Engineering 2019 1:29

    Content type: Research Article

    Published on:

  26. Adipose tissue is a vital tissue in mammals that functions to insulate our bodies, regulate our internal thermostat, protect our organs, store energy (and burn energy, in the case of beige and brown fat), and ...

    Authors: Connor S. Murphy, Lucy Liaw and Michaela R. Reagan

    Citation: BMC Biomedical Engineering 2019 1:27

    Content type: Review

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  27. Since nuclei segmentation in histopathology images can provide key information for identifying the presence or stage of a disease, the images need to be assessed carefully. However, color variation in histopat...

    Authors: Hwejin Jung, Bilal Lodhi and Jaewoo Kang

    Citation: BMC Biomedical Engineering 2019 1:24

    Content type: Research article

    Published on:

  28. Leg-press devices are one of the most widely used training tools for musculoskeletal strengthening of the lower-limbs, and have demonstrated important cardiopulmonary benefits for healthy and patient populatio...

    Authors: Farouk Chrif, Tobias Nef and Kenneth J Hunt

    Citation: BMC Biomedical Engineering 2019 1:26

    Content type: Research Article

    Published on:

  29. Optical mapping of transmembrane voltage and intracellular calcium is a powerful tool for investigating cardiac physiology and pathophysiology. However, simultaneous dual mapping of two fluorescent probes rema...

    Authors: Rafael Jaimes III, Damon McCullough, Bryan Siegel, Luther Swift, James Hiebert, Daniel McInerney and Nikki Gillum Posnack

    Citation: BMC Biomedical Engineering 2019 1:25

    Content type: Research article

    Published on:

  30. Accurate spasticity assessment provides an objective evaluation index for the rehabilitation treatment of patients with spasticity, and the key is detecting stretch reflex onset. The surface electromyogram of ...

    Authors: Mingjia Du, Baohua Hu, Feiyun Xiao, Ming Wu, Zongjun Zhu and Yong Wang

    Citation: BMC Biomedical Engineering 2019 1:23

    Content type: Research article

    Published on:

  31. Many people suffer from movement disability due to amputation or neurological diseases. Fortunately, with modern neurotechnology now it is possible to intercept motor control signals at various points along th...

    Authors: Wing-kin Tam, Tong Wu, Qi Zhao, Edward Keefer and Zhi Yang

    Citation: BMC Biomedical Engineering 2019 1:22

    Content type: Review

    Published on:

  32. In virtual reality (VR) applications such as games, virtual training, and interactive neurorehabilitation, one can employ either the first-person user perspective or the third-person perspective to perceive th...

    Authors: Juan Trelles Trabucco, Andrea Rottigni, Marco Cavallo, Daniel Bailey, James Patton and G. Elisabeta Marai

    Citation: BMC Biomedical Engineering 2019 1:21

    Content type: Research article

    Published on:

  33. Stroke rehabilitation often uses the motor relearning concept that require patients to perform active practice of skill-specific training and to receive feedback. Treadmill training augmented with real-time vi...

    Authors: Chanwit Phongamwong, Philip Rowe, Karen Chase, Andrew Kerr and Lindsay Millar

    Citation: BMC Biomedical Engineering 2019 1:20

    Content type: Research article

    Published on:

  34. A growing need exists for neuroscience platforms that can perform simultaneous chronic recording and stimulation of neural tissue in animal models in a telemetry-controlled fashion with signal processing for a...

    Authors: John T. Ramshur, Bashir I. Morshed, Amy L. de Jongh Curry and Robert S. Waters

    Citation: BMC Biomedical Engineering 2019 1:19

    Content type: Methodology article

    Published on:

  35. Organoids derived from induced pluripotent stem (iPS) or embryonic stem (ES) cells have been evaluated as in vitro models of development and disease. However, maintaining these cells under long-term static cul...

    Authors: Sachiko Sekiya, Tetsutaro Kikuchi and Tatsuya Shimizu

    Citation: BMC Biomedical Engineering 2019 1:15

    Content type: Methodology article

    Published on:

  36. Therapy resistant ulcers are wounds that remain open for a long time period and often arise from chronic venous disease, prolonged pressure or diabetes. For healing of chronic wounds, revitalization of the ine...

    Authors: Hanneke N. Monsuur, Ester M. Weijers, Susan Gibbs and Lenie J. van den Broek

    Citation: BMC Biomedical Engineering 2019 1:18

    Content type: Research article

    Published on:

  38. Excessive extracellular matrix (ECM) deposition is a hallmark feature in fibrosis and tissue remodelling diseases. Typically, mesenchymal cells will produce collagens under standard 2D cell culture conditions,...

    Authors: Robert B. Good, Jessica D. Eley, Elaine Gower, Genevieve Butt, Andrew D. Blanchard, Andrew J. Fisher and Carmel B. Nanthakumar

    Citation: BMC Biomedical Engineering 2019 1:14

    Content type: Research article

    Published on:

  39. Mesenchymal stromal cells (MSCs) are widely used in clinical trials for bone repair and regeneration. Despite previous evidence showing a prominent osteogenic potential of 2D cultured CD271 enriched MSCs, the ...

    Authors: Sylvia Müller, Lyndsey Nicholson, Naif Al Harbi, Elena Mancuso, Elena Jones, Anne Dickinson, Xiao Nong Wang and Kenneth Dalgarno

    Citation: BMC Biomedical Engineering 2019 1:16

    Content type: Research

    Published on:

    The Correction to this article has been published in BMC Biomedical Engineering 2019 1:34

  40. Due to the presence of high noise level in tomographic series of energy filtered transmission electron microscopy (EFTEM) images, alignment and 3D reconstruction steps become so difficult. To improve the align...

    Authors: Soumia Sid Ahmed, Zoubeida Messali, Larbi Boubchir, Ahmed Bouridane, Sergio Marco and Cédric Messaoudi

    Citation: BMC Biomedical Engineering 2019 1:13

    Content type: Research article

    Published on:

  41. In this paper, we focus on robots used for laparoscopic surgery, which is one of the most active areas for research and development of surgical robots. We introduce research and development of laparoscope-hold...

    Authors: Kenji Kawashima, Takahiro Kanno and Kotaro Tadano

    Citation: BMC Biomedical Engineering 2019 1:12

    Content type: Review

    Published on:

  42. Currently there are no standard models with which to evaluate the biomechanical performance of calcified tissue adhesives, in vivo. We present, herein, a pre-clinical murine distal femoral bone model for evaluati...

    Authors: Philip Procter, Michael Pujari-Palmer, Gry Hulsart-Billström, David Wenner, Gerard Insley, Sune Larsson and Håkan Engqvist

    Citation: BMC Biomedical Engineering 2019 1:11

    Content type: Methodology article

    Published on:

  43. Advancement in polymer technologies, facilitated predominantly through chemical engineering approaches or through the identification and utilization of novel renewable resources, has been a steady focus of bio...

    Authors: Katarzyna Krukiewicz, Jorge Fernandez, Małgorzata Skorupa, Daria Więcławska, Anup Poudel, Jose-Ramon Sarasua, Leo R. Quinlan and Manus J. P. Biggs

    Citation: BMC Biomedical Engineering 2019 1:9

    Content type: Research article

    Published on:

  44. In Photoacoustic imaging (PAI), the most prevalent beamforming algorithm is delay-and-sum (DAS) due to its simple implementation. However, it results in a low quality image affected by the high level of sidelo...

    Authors: Moein Mozaffarzadeh, Bahador Makkiabadi, Maryam Basij and Mohammad Mehrmohammadi

    Citation: BMC Biomedical Engineering 2019 1:10

    Content type: Research article

    Published on:

  46. Frailty assessment is a critical approach in assessing the health status of older people. The clinical tools deployed by geriatricians to assess frailty can be grouped into two categories; using a questionnair...

    Authors: Yasmeen Naz Panhwar, Fazel Naghdy, Golshah Naghdy, David Stirling and Janette Potter

    Citation: BMC Biomedical Engineering 2019 1:7

    Content type: Research article

    Published on:

  48. Adhesions represent a major burden in clinical practice, particularly following abdominal, intrauterine, pericardial and tendon surgical procedures. Adhesions are initiated by a disruption in the epithelial or...

    Authors: Héctor Capella-Monsonís, Stephen Kearns, Jack Kelly and Dimitrios I. Zeugolis

    Citation: BMC Biomedical Engineering 2019 1:5

    Content type: Review

    Published on:

  50. This editorial accompanies the launch of BMC Biomedical Engineering, a new open access, peer-reviewed journal within the BMC series, which seeks to publish articles on all aspects of biomedical engineering. As on...

    Authors: Alexandros Houssein, Alan Kawarai Lefor, Antonio Veloso, Zhi Yang, Jong Chul Ye, Dimitrios I. Zeugolis and Sang Yup Lee

    Citation: BMC Biomedical Engineering 2019 1:1

    Content type: Editorial

    Published on:

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